JMIR Bioinformatics and Biotechnology
Methods, devices, web-based platforms, open data and open software tools for big data analytics, understanding biological/medical data, and information retrieval in biology and medicine.
JMIR Bioinformatics and Biotechnology (JBB) is a new open access journal from JMIR Publications, the leading publisher for technology in health and medicine. JBB is a new sister journal of JMIR, the leading journal in medicine, ehealth and health services research in the Internet age.
We are currently seeking academic leaders in this field to apply as acquistion editors or section editors for Editorial Board positions. Among the EB, we will select an editor-in-chief.
Prequisites include a scholarly track-record, demonstrated by being a first author on peer-reviewed publications and having served as peer-reviewer (preferably this should include JMIR journals. Applicants can self-assign themselves to papers to be peer-reviewed at JMIR Preprints). Please include a list of publications as well as journals you reviewed for.
To apply, please read these instructions and submit the application form including a brief description of your expertise and interests.
Chronic kidney disease is a major public health issue, with about 13% of the general adult population and 30% of the elderly affected. Patients in the last stage of this disease have an almost uniquely high risk of death and cardiovascular events, with reduced adherence to therapy representing an additional risk factor for cardiovascular morbidity and mortality. Considering the increased penetration of mobile phones, a mobile app could educate patients to autonomously monitor cardiorenal risk factors.
The mammalian immune system is able to generate antibodies against a huge variety of antigens, including bacteria, viruses, and toxins. The ultradeep DNA sequencing of rearranged immunoglobulin genes has considerable potential in furthering our understanding of the immune response, but it is limited by the lack of a high-throughput, sequence-based method for predicting the antigen(s) that a given immunoglobulin recognizes.
Treatment discontinuation (TD) is one of the major prognostic issues in diabetes care, and several models have been proposed to predict a missed appointment that may lead to TD in patients with diabetes by using binary classification models for the early detection of TD and for providing intervention support for patients. However, as binary classification models output the probability of a missed appointment occurring within a predetermined period, they are limited in their ability to estimate the magnitude of TD risk in patients with inconsistent intervals between appointments, making it difficult to prioritize patients for whom intervention support should be provided.
Since the start of the COVID-19 pandemic, health policymakers globally have been attempting to predict an impending wave of COVID-19. India experienced a devastating second wave of COVID-19 in the late first week of May 2021. We retrospectively analyzed the viral genomic sequences and epidemiological data reflecting the emergence and spread of the second wave of COVID-19 in India to construct a prediction model.
In recent years, thanks to the rapid development of next-generation sequencing (NGS) technology, an entire human genome can be sequenced in a short period. As a result, NGS technology is now being widely introduced into clinical diagnosis practice, especially for diagnosis of hereditary disorders. Although the exome data of single-nucleotide variant (SNV) can be generated using these approaches, processing the DNA sequence data of a patient requires multiple tools and complex bioinformatics pipelines.
Emergency department crowding continues to threaten patient safety and cause poor patient outcomes. Prior models designed to predict hospital admission have had biases. Predictive models that successfully estimate the probability of patient hospital admission would be useful in reducing or preventing emergency department “boarding” and hospital “exit block” and would reduce emergency department crowding by initiating earlier hospital admission and avoiding protracted bed procurement processes.
Hashimoto thyroiditis (HT) is an autoimmune thyroid disease and the leading cause of hypothyroidism in areas with sufficient iodine intake. The quality-of-life impact and financial burden of hypothyroidism and HT highlight the need for additional research investigating the disease etiology with the aim of revealing potential modifiable risk factors.
Femoral neck fracture (FNF) accounts for approximately 3.58% of all fractures in the entire body, exhibiting an increasing trend each year. According to a survey, in 1990, the total number of hip fractures in men and women worldwide was approximately 338,000 and 917,000, respectively. In China, FNFs account for 48.22% of hip fractures. Currently, many studies have been conducted on postdischarge mortality and mortality risk in patients with FNF. However, there have been no definitive studies on in-hospital mortality or its influencing factors in patients with severe FNF admitted to the intensive care unit.
Venous thromboembolism (VTE) is a preventable, common vascular disease that has been estimated to affect up to 900,000 people per year. It has been associated with risk factors such as recent surgery, cancer, and hospitalization. VTE surveillance for patient management and safety can be improved via natural language processing (NLP). NLP tools have the ability to access electronic medical records, identify patients that meet the VTE case definition, and subsequently enter the relevant information into a database for hospital review.
Physical activity is emerging as an outcome measure. Accelerometers have become an important tool in monitoring physical behavior, and newer analytical approaches of recognition methods increase the degree of details. Many studies have achieved high performance in the classification of physical behaviors through the use of multiple wearable sensors; however, multiple wearables can be impractical and lower compliance.
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