JMIR Bioinformatics and Biotechnology

Methods, devices, web-based platforms, open data and open software tools for big data analytics, understanding biological/medical data, and information retrieval in biology and medicine.


JMIR Bioinformatics and Biotechnology (JBB) is a new open access journal from JMIR Publications, the leading publisher for technology in health and medicine. JBB is a new sister journal of JMIR, the leading journal in medicine, ehealth and health services research in the Internet age. 

We are currently seeking academic leaders in this field to apply as acquistion editors or section editors for Editorial Board positions. Among the EB, we will select an editor-in-chief

Prequisites include a scholarly track-record, demonstrated by being a first author on peer-reviewed publications and having served as peer-reviewer (preferably this should include JMIR journals. Applicants can self-assign themselves to papers to be peer-reviewed at JMIR Preprints). Please include a list of publications as well as journals you reviewed for.

To apply, please read these instructions and submit the application form including a brief description of your expertise and interests. 

Recent Articles

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Venous thromboembolism (VTE) is a preventable, common vascular disease that has been estimated to affect up to 900,000 people per year. It has been associated with risk factors such as recent surgery, cancer, and hospitalization. VTE surveillance for patient management and safety can be improved via natural language processing (NLP). NLP tools have the ability to access electronic medical records, identify patients that meet the VTE case definition, and subsequently enter the relevant information into a database for hospital review.

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Original Article

Physical activity is emerging as an outcome measure. Accelerometers have become an important tool in monitoring physical behavior, and newer analytical approaches of recognition methods increase the degree of details. Many studies have achieved high performance in the classification of physical behaviors through the use of multiple wearable sensors; however, multiple wearables can be impractical and lower compliance.

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Original Article

Since the first appearance of SARS-CoV-2 in China in December 2019, the world witnessed the emergence of the SARS-CoV-2 outbreak. Due to the high transmissibility rate of the virus, there is an urgent need to design and develop vaccines against SARS-CoV-2 to prevent more cases affected by the virus.

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Review

Digital phenotyping is the real-time collection of individual-level active and passive data from users in naturalistic and free-living settings via personal digital devices, such as mobile phones and wearable devices. Given the novelty of research in this field, there is heterogeneity in the clinical use cases, types of data collected, modes of data collection, data analysis methods, and outcomes measured.

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Original Article

Alagille syndrome is an autosomal dominant disorder associated with variable clinical phenotypic features including cholestasis, congenital heart defects, vertebral defects, and dysmorphic facies.

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Original Article

Long noncoding RNAs (lncRNAs) are noncoding RNA transcripts greater than 200 nucleotides in length and are known to play a role in regulating the transcription of genes involved in vital cellular functions. We hypothesized the disease process in dysferlinopathy is linked to an aberrant expression of lncRNAs and messenger RNAs (mRNAs).

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Original Article

Large amounts of biological data have been generated over the last few decades, encouraging scientists to look for connections between genes that cause various diseases. Clustering illustrates such a relationship between numerous species and genes. Finding an appropriate distance-linkage metric to construct clusters from diverse biological data sets has thus become critical. Pleiotropy is also important for a gene’s expression to vary and create varied consequences in living things. Finding the pleiotropy of genes responsible for various diseases has become a major research challenge.

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Original Article

A recent global outbreak of COVID-19 caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) created a pandemic and emerged as a potential threat to humanity. The analysis of virus genetic composition has revealed that the spike protein, one of the major structural proteins, facilitates the entry of the virus to host cells.

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Original Article

The recent emergence of COVID-19 has caused an immense global public health crisis. The etiological agent of COVID-19 is the novel coronavirus SARS-CoV-2. More research in the field of developing effective vaccines against this emergent viral disease is indeed a need of the hour.

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Genome Analysis and Visualization

Early sequencing and quick analysis of the SARS-CoV-2 genome have contributed to the understanding of the dynamics of COVID-19 epidemics and in designing countermeasures at a global level.

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Original Article

Type 2 diabetes mellitus (T2DM) is a metabolic disorder with severe comorbidities. A multiomics approach can facilitate the identification of novel therapeutic targets and biomarkers with proper validation of potential microRNA (miRNA) interactions.

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Original Article

Colorectal and prostate cancers are the most common types of cancer in men worldwide. To diagnose colorectal and prostate cancer, a pathologist performs a histological analysis on needle biopsy samples. This manual process is time-consuming and error-prone, resulting in high intra- and interobserver variability, which affects diagnosis reliability.

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