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Structural biology and molecular modeling (9) New Methods (1784) Tools, Programs and Algorithms (581) Infectious Diseases (non-STD/STI) (1923) Theme Issue: Novel Coronavirus (COVID-19) Outbreak Rapid Reports (2030) Outbreak and Pandemic Preparedness and Management (1960) Genome Analysis and Visualization (26) COVID-19 Vaccination (274) Genomic and Evolutionary Analysis in COVID-19 (15)

Published on in Vol 6 (2025)

This is a member publication of Tulane University

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/73637, first published .
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Structural and Functional Impacts of SARS-CoV-2 Spike Protein Mutations: Insights From Predictive Modeling and Analytics

Structural and Functional Impacts of SARS-CoV-2 Spike Protein Mutations: Insights From Predictive Modeling and Analytics

Authors of this article:

Edem K Netsey1 Author Orcid Image ;   Samuel M Naandam2 Author Orcid Image ;   Joseph Asante Jnr3 Author Orcid Image ;   Kuukua E Abraham4 Author Orcid Image ;   Aayire C Yadem5 Author Orcid Image ;   Gabriel Owusu6 Author Orcid Image ;   Jeffrey G Shaffer7 Author Orcid Image ;   Sudesh K Srivastav7 Author Orcid Image ;   Seydou Doumbia8 Author Orcid Image ;   Ellis Owusu-Dabo9 Author Orcid Image ;   Chris E Morkle10 Author Orcid Image ;   Desmond Yemeh11 Author Orcid Image ;   Stephen Manortey12 Author Orcid Image ;   Ernest Yankson2 Author Orcid Image ;   Mamadou Sangare13 Author Orcid Image ;   Samuel Kakraba7, 11 Author Orcid Image
Article Authors Cited by (7) Tweetations Metrics

Journals

  1. Wenzheng H, Agyemang E, Srivastav S, Shaffer J, Kakraba S. Artificial Intelligence–Enhanced Multi-Algorithm R Shiny Application for Predictive Modeling and Analytics: Case Study of Alzheimer Disease Diagnostics. JMIR Aging 2025;8:e70272 View
  2. Netsey E, Naandam S, Asante Jnr J, Abraham K, Yadem A, Owusu G, Shaffer J, Srivastav S, Doumbia S, Owusu-Dabo E, Morkle C, Yemeh D, Manortey S, Yankson E, Sangare M, Kakraba S. Correction: Structural and Functional Impacts of SARS-CoV-2 Spike Protein Mutations: Insights From Predictive Modeling and Analytics. JMIR Bioinformatics and Biotechnology 2025;6:e89673 View
  3. Kakraba S, Agyemang E, Shmookler Reis R. Accelerating Discovery of Leukemia Inhibitors Using AI-Driven Quantitative Structure-Activity Relationship: Algorithm Development and Validation. JMIR AI 2026;5:e81552 View
  4. Kakraba S, Agyemang E, Srivastav S. Cognitive sovereignty and decolonial public health: reclaiming epistemic authority in the global AI era. Frontiers in Public Health 2026;14 View
  5. Kakraba S, Yadem A, Abraham K, Chaudhry F, Agyemang E. Unraveling protein secrets: machine learning unveils novel biologically significant associations among amino acids. Network Modeling Analysis in Health Informatics and Bioinformatics 2026;15(1) View
  6. Smatti M, Al-Khatib H, Suleman M, Nizar M, Khalid H, Ismail R, Nasrallah G, Yassine H. Functional and structural characterization of the SARS-CoV-2 spike N481K mutation. Archives of Virology 2026;171(7) View
  7. Chung H, Jin Y, Kim S, Park S, Chung H, Hwang S, Ko S, Nguyen V, Lee J. Structural and Computational Insights into the Attenuated Innate Immune Recognition of the SARS-CoV-2 N15 Lineage, an Early-Pandemic Variant. Computational and Structural Biotechnology Journal 2026;35(1) View